Clinically proven skin regeneration delivered safely by a qualified medical professional.
Plinest is a medical-grade polynucleotide treatment designed to repair, hydrate, and improve overall skin quality. It is widely recognised for its ability to improve elasticity, smoothness, and skin health.
At AJ Aesthetics, treatments are carried out by a qualified nurse prescriber, ensuring safe, compliant, and personalised care.
Plinest is a polynucleotide injectable derived from purified DNA fragments, designed to stimulate skin regeneration and repair.
It works by improving cell turnover, boosting collagen production, and enhancing skin hydration — making it ideal for both preventative and corrective treatments.
Plinest is suitable for a wide range of skin types and concerns, including:
• Dehydrated or tired-looking skin
• Fine lines and early ageing
• Loss of elasticity
• Uneven texture or skin damage
• Under-eye rejuvenation
Suitability is always assessed during consultation.
Plinest stimulates skin regeneration at a cellular level, helping to:
• Improve hydration and elasticity
• Strengthen the skin structure
• Support collagen and elastin production
• Improve skin tone and texture
• Restore a healthy, radiant appearance
Results build gradually for natural-looking improvement.
Each treatment uses approximately 2ml of product.
For best results:
• 2–3 sessions are recommended, spaced 3–4 weeks apart
• Maintenance is recommended every 4–6 months
This may vary depending on individual skin needs.
Do I need to have fine lines and wrinkles for this treatment?
What to expect during treatment?
Does the treatment hurt?
What should I avoid before treatment?
What should I avoid after treatment?
• Avoid touching the area or applying makeup for 24 hours
• Avoid alcohol and swimming for 48 hours
• Avoid heat (saunas, steam), facials, and active skincare (retinol, acids, vitamin C) for 5–7 days
• Avoid other cosmetic treatments for 1 week
Is there any downtime?
There is minimal downtime. Mild redness, swelling, or small bumps at injection sites may occur and usually settle within 24–72 hours. Bruising is possible, so allow up to two weeks before important events.
When will I see results?
Some improvement in hydration and skin quality can be seen within a few days, with continued improvement over several weeks as the skin regenerates. Full results are typically seen after a course of treatments.
Do I need two sessions?
Yes, a course of 2–3 treatments spaced 3–4 weeks apart is recommended for optimal results. Improvements may be seen after the first session, but a full course provides longer-lasting benefits.
How long do results last?
Results typically last around 4–6 months. Maintenance treatments are recommended to keep the skin healthy and results consistent.
Does it replace filler?
No. Polynucleotides are not volumising treatments. They improve skin quality, hydration, and repair, rather than adding volume or structure like dermal fillers.
Can it be combined with other treatments?
Yes. Polynucleotides can be combined with other treatments such as skin boosters, anti-wrinkle treatments, and dermal fillers to enhance overall results. A personalised treatment plan will be created during consultation.